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Updated: Aug 20, 2026

Full-Endoscopic Surgery for Hypothalamic Hamartoma Resection
Published on: April 12, 2024
A case of recurrent and synchronous fibrous hamartoma of infancy
Reisuke Imaji1, Takahumi Goto, Yusuke Takahashi
1Department of Paediatric Surgery, National Okayama Medical Centre, 1711-1, Tamasu, Okayama City, Okayama 701-1192, Japan.
Insights
Fibrous hamartoma of infancy (FHI) is a rare pediatric tumor. This case highlights FHI recurrence, emphasizing its consideration in the differential diagnosis of infant subcutaneous masses.
Area of Science:
- Pediatric Oncology
- Dermatopathology
- Surgical Pathology
Background:
- Fibrous hamartoma of infancy (FHI) is a rare, benign soft tissue tumor typically presenting in infants and young children.
- It characteristically appears as a rapidly growing, painless mass, often on the upper extremities, trunk, or head and neck.
Observation:
- A 6-month-old male presented with a gradually enlarging buttock mass, diagnosed as FHI.
- The lesion recurred 18 months after initial excision and required reexcision 41 months post-initial operation.
Findings:
- Histopathological examination of both the primary and recurrent masses confirmed the diagnosis of FHI.
- The recurrent tumor exhibited characteristic FHI features, including a triphasic pattern of fibrous, myxoid, and smooth muscle components.
Implications:
- Recurrence of FHI, though uncommon, necessitates thorough surgical excision and long-term follow-up.
- FHI should be included in the differential diagnosis for subcutaneous masses in young children to ensure appropriate management.
Abstract:
We retrospectively reviewed the chart of a patient with recurrent fibrous hamartoma of infancy (FHI). This lesion presented as a gradually enlarging mass on the child's buttock. The child, a 6-month-old male, was followed up, and at 19 months of age the mass was excised. Eighteen months after the initial operation, a local recurrence was noticed. Forty-one months after the initial operation, reexcision was performed. Both masses demonstrated the characteristic features of FHI, which should be considered in the differential diagnosis of subcutaneous mass in young children.
