Related Experiment Video
Updated: Aug 20, 2026

Correlative Light and Electron Microscopy to Study Microglial Interactions with β-Amyloid Plaques
Published on: June 1, 2016
The role of electron microscopy in neuropathology
1Division of Neuropathology, Department of Pathology, Montefiore Medical Center, Bronx, NY, 10467-2094, USA. ahirano@montefiore.org
Abstract:
The electron microscope has been an essential instrument for elucidating the morphology of cells and tissue. Fine structural investigation of nervous tissue has disclosed numerous new findings, which were once invisible. In this communication I present my personal perspective on the role of electron microscopy in neuropathology through the presentation of selected electron microscopic projects engaged in our institution. These include brain edema, structural analysis of the myelin in the central nervous system, endodermal cysts in the central nervous system, aberrant synaptic development, toxoplasmosis in AIDS, and Hirano bodies.
Related Concept Videos
Overview of Electron Microscopy
Cryo-electron Microscopy
Immunogold Electron Microscopy
Preparation of Samples for Electron Microscopy
Transmission Electron Microscopy
