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Susceptibility of different eukaryotic cell lines to SARS-coronavirus

K Hattermann1, M A Müller, A Nitsche

  • 1Robert Koch-Institut, Center for Biological Safety 1, Berlin, Germany.

Archives of Virology
|January 13, 2005
PubMed

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Coronaviruses, including the severe acute respiratory syndrome coronavirus (SARS-CoV), are enveloped viruses characterized by their single-stranded, positive-sense RNA genome and helical nucleocapsid structure. The hallmark of these viruses is their club-shaped spike (S) glycoproteins that protrude from the viral envelope, facilitating attachment to host cells. Typically, coronaviruses infect the upper respiratory tract, often causing mild or asymptomatic disease. However, certain strains like...