Related Experiment Video
Updated: Aug 10, 2026
09:57
A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit
Published on: July 13, 2019
Restoring patency of long-term central venous access devices
Summary
Central venous access devices (CVADs) are crucial for long-term therapies but prone to occlusion. Selecting the right pharmacologic agent is essential for restoring CVAD patency.
Area of Science:
- Vascular Access
- Pharmacology
- Infusion Therapy
Background:
- Increasing use of complex infusion therapies necessitates long-term central venous access.
- Central venous access devices (CVADs) are vital for therapies like parenteral nutrition, antibiotics, and chemotherapy.
- Multiple therapies via CVADs heighten the risk of catheter occlusion.
Purpose of the Study:
- To review the causes of central venous access device (CVAD) occlusion.
- To evaluate pharmacologic agents used for restoring CVAD patency.
- To emphasize the importance of thorough evaluation for selecting appropriate occlusion treatment.
Main Methods:
- Literature review of causes for CVAD occlusion.
- Analysis of pharmacologic agents used to treat occluded CVADs.
- Discussion of factors influencing agent selection for patency restoration.
Main Results:
- Catheter occlusion causes include thrombosis, lipid deposits, and precipitation of medications/electrolytes.
- Pharmacologic agents like thrombolytics, ethyl alcohol, hydrochloric acid, and sodium bicarbonate are used.
- Effective treatment requires understanding occlusion etiology and agent properties.
Conclusions:
- CVAD occlusion is a common complication of complex infusion therapies.
- A range of pharmacologic agents can be employed to restore catheter patency.
- Tailored selection of pharmacologic agents based on comprehensive CVAD assessment is critical for successful outcomes.
Related Concept Videos
01:27Parentral Nutrition: Centeral and Peripheral Parental Nutrition
Parenteral Nutrition (PN) delivers essential nutrients directly into the bloodstream, bypassing the digestive system. It is commonly used for individuals with severe digestive disorders or conditions that prevent normal nutrient absorption.
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
01:23Peripheral Artery Disease V: Postoperative Nursing Management
During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
01:22Aneurysm IV: Nursing Management
Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...
01:25Hemodialysis I: Introduction
Hemodialysis (HD) is a medical treatment that artificially removes waste products, excess fluids, and toxins from the blood when the kidneys are no longer able to perform these functions effectively. In this process, blood is filtered through a semipermeable membrane, allowing for the selective removal of waste while preserving necessary components like blood cells and proteins. Hemodialysis is typically performed in patients with end-stage renal disease (ESRD) or severe kidney...