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Gout epidemiology: results from the UK General Practice Research Database, 1990-1999
T R Mikuls1, J T Farrar, W B Bilker
1Department of Medicine, University of Nebraska Medical Center and Omaha VA Medical Center, Omaha, NE, USA.
Annals of the Rheumatic Diseases
|January 14, 2005
Summary
Gout is common in the UK, especially in older men, with stable incidence rates throughout the 1990s. This study analyzed UK general practice data to understand gout epidemiology and treatment patterns.
Area of Science:
- Epidemiology
- Rheumatology
- Public Health
Background:
- Gout is a prevalent inflammatory arthritis, particularly affecting older populations.
- Understanding gout epidemiology and treatment is crucial for public health management in the United Kingdom.
Purpose of the Study:
- To investigate the epidemiology of gout, including incidence and prevalence, within the UK.
- To examine trends in gout treatment and identify associated comorbid conditions.
Main Methods:
- Utilized data from the UK General Practice Research Database (1990-1999).
- Analyzed physician diagnoses and drug codes to assess gout incidence, prevalence, and treatment.
- Compared comorbidities in gout patients versus osteoarthritis patients, adjusting for age and sex.
Main Results:
- Gout incidence remained stable from 1990-1999, with prevalence at 1.4% in 1999, rising to 7% in men over 65.
- Non-steroidal anti-inflammatory drug use for gout treatment declined over the decade.
- Gout patients showed higher rates of cardiovascular disease, hypertension, diabetes, and chronic renal failure compared to osteoarthritis patients.
Conclusions:
- Gout is a common condition in the UK, disproportionately affecting older men.
- The incidence of gout in the UK appears to have remained consistent during the 1990s.
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