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Updated: Aug 20, 2026

Murine Distal Colostomy, A Novel Model of Diversion Colitis in C57BL/6 Mice
Published on: July 12, 2018
Colonic perforation in collagenous colitis: an unusual complication
Johan Bohr1, Lars-Göran Larsson, Sune Eriksson
1Department of Medicine, Division of Gastroenterology, Orebro University Hospital, Orebro, Sweden. johan.bohr@orebroll.se
Abstract:
Collagenous colitis is generally regarded as a benign disease with few serious complications. We report two women with collagenous colitis who presented with colonic perforation, one spontaneously and one 7 days after a barium enema, and a review of the literature. Including the present cases, 13 patients with collagenous colitis and colonic perforation have been reported, in two patients spontaneously and in 11 patients after a colonoscopy or barium enema. All were operated on except one patient who recovered after medical treatment. The pathogenesis of this complication is unknown. We propose that there might be a connection between mucosal tears and colonic perforation in collagenous colitis.
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