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Acute diarrhea, a common gastrointestinal disturbance, is characterized by the rapid evacuation of fluid stools, leading to an excessive weight in fluid. This condition typically arises from disorders affecting intestinal water and electrolyte transport. It can be triggered by an increased osmotic load within the intestine, excessive secretion of electrolytes and water, mucosal exudation of protein and fluid, or altered intestinal motility. The primary risks of acute diarrhea are dehydration...
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Related Experiment Video

Updated: Feb 25, 2026

A Soluble Tetrazolium-Based Reduction Assay to Evaluate the Effect of Antibodies on Candida tropicalis Biofilms
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Candida and antibiotic-associated diarrhoea.

R Krause, E C Reisinger

    Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases
    |January 15, 2005
    PubMed
    Summary

    The role of Candida in antibiotic-associated diarrhoea (AAD) remains controversial. Current evidence does not convincingly support Candida as a cause of AAD in adults, despite increased counts sometimes being observed.

    Area of Science:

    • Microbiology
    • Gastroenterology
    • Clinical Medicine

    Background:

    • Candida species are normal gastrointestinal flora, with small numbers typically considered non-pathogenic.
    • Increased Candida counts in stool have been historically associated with antibiotic-associated diarrhoea (AAD).

    Discussion:

    • The physiological presence of Candida complicates its role in AAD.
    • Recent studies have challenged the direct causative link between Candida and AAD.

    Key Insights:

    • There is a lack of convincing evidence to establish Candida as a cause of AAD in adult patients.
    • The association between elevated Candida levels and diarrhoea in antibiotic-treated individuals is not definitively proven.

    Outlook:

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  • Further research is needed to clarify the precise role, if any, of Candida in AAD.
  • Differential diagnosis of AAD should consider multiple potential etiologies beyond Candida.