Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Automatic wave form classification of extracellular multineuron recordings.

R F Jansen1, A Ter Maat

  • 1Department of Biology, Vrije Universiteit, Amsterdam, The Netherlands.

Journal of Neuroscience Methods
|February 1, 1992
PubMed
Summary

This study presents a PC-based method to automatically reconstruct individual neuron spike trains from extracellular recordings. The approach uses a template-finding algorithm to accurately identify and separate neuronal signals without prior waveform knowledge.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Single-cell analysis of peptide expression and electrophysiology of right parietal neurons involved in male copulation behavior of a simultaneous hermaphrodite.

Invertebrate neuroscience : IN·2015
Same author

The distinction between retractor and protractor muscles of the freshwater snail's male organ has no physiological basis.

The Journal of experimental biology·2009
Same author

Spatio-temporal dynamics of the egg-laying-inducing peptides during an egg-laying cycle: a semiquantitative matrix-assisted laser desorption/ionization mass spectrometry approach.

Journal of neurochemistry·2004
Same author

"Allohormones": a class of bioactive substances favoured by sexual selection.

Journal of comparative physiology. A, Sensory, neural, and behavioral physiology·2001
Same author

NPY in invertebrates: molecular answers to altered functions during evolution.

Peptides·2001
Same author

A conserved location for the central nervous system control of mating behaviour in gastropod molluscs: evidence from a terrestrial snail.

The Journal of experimental biology·2000

Area of Science:

  • Neuroscience
  • Computational Neuroscience
  • Signal Processing

Background:

  • Extracellular recordings capture signals from multiple neurons simultaneously.
  • Accurate reconstruction of individual neuron activity is crucial for understanding neural circuits.
  • Existing methods may require prior knowledge of neuronal waveform shapes.

Purpose of the Study:

  • To develop a fully automatic method for reconstructing individual spike trains.
  • To enable accurate spike train separation from multineuron extracellular recordings.
  • To eliminate the need for pre-defined waveform templates.

Main Methods:

  • A PC-based computational approach was developed.
  • A fully automatic template-finding algorithm was employed.

Related Experiment Videos

  • The algorithm utilizes the entire dataset to extract spike waveform templates.
  • Individual spike trains are reconstructed in a subsequent step.

    • Main Results:

    • Successful reconstruction of individual spike trains from complex extracellular recordings.
    • Demonstration of an automatic template-finding algorithm.
    • Validation of the method's efficacy without prior waveform information.

    Conclusions:

    • The described PC-based method offers an automated solution for spike train reconstruction.
    • This technique enhances the analysis of multineuron extracellular recordings.
    • The approach provides a valuable tool for computational neuroscience research.