Insight into pollutant bioavailability and toxicity using Raman confocal microscopy
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An Integrated Raman Spectroscopy and Mass Spectrometry Platform to Study Single-Cell Drug Uptake, Metabolism, and Effects
Published on: January 9, 2020
Andrew C Singer1, Wei E Huang, Jana Helm
1Environmental Biotechnology Section, Centre for Ecology and Hydrology-Oxford, Mansfield Road, Oxford, OX1 3SR, UK. acsi@ceh.ac.uk
Journal of Microbiological Methods
|January 15, 2005
Abstract:
Raman confocal microscopy was used to discriminate between cultures of Burkholderia xenovorans LB400 exposed to four different common environmental pollutants: phenanthrene, dodecane, 3-chlorobiphenyl and pentachlorophenol. Evidence is presented for the application of Raman spectroscopy as a bioassay for pollutant bioavailability and toxicity.
