Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Bone marrow imaging using STIR at 0.5 and 1.5 T.

K M Jones1, E C Unger, P Granstrom

  • 1Department of Radiology, University of Arizona Health Sciences Center, Tucson 85724.

Magnetic Resonance Imaging
|January 1, 1992
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Aspartate aminotransferase is required for <i>Salmonella</i> expansion in the inflamed gut via TCA anaplerosis.

bioRxiv : the preprint server for biology·2026
Same author

Aspartate aminotransferase is required for <i>Salmonella</i> expansion in the inflamed gut via TCA anaplerosis.

Infection and immunity·2026
Same author

Color-switching in an optical parametric oscillator using a phase-conjugate mirror.

Optics express·2024
Same author

Cdk12 maintains the integrity of adult axons by suppressing actin remodeling.

Cell death discovery·2023
Same author

Familial chilblain lupus in a child with heterozygous mutation in SAMHD1 and normal interferon signature.

The British journal of dermatology·2021
Same author

Incidence of healthcare-associated infections in patients with fever during the first 48 hours after decannulation from veno-venous extracorporeal membrane oxygenation.

Perfusion·2020
Same journal

Repeatability of an MRI protocol for generating habitats based on cellularity, perfusion, and hypoxia in a murine model of glioma.

Magnetic resonance imaging·2026
Same journal

Association between CMR-derived pulmonary artery pulse wave velocity and pulmonary risk factors: the multi-ethnic study of atherosclerosis COPD study.

Magnetic resonance imaging·2026
Same journal

Systematic comparison of MPRAGE and BRAVO T1-weighted MRI pulse sequences and brain morphometry in high-risk young adults.

Magnetic resonance imaging·2026
Same journal

Foot dynamic contrast-enhanced MRI for assessing microcirculatory changes after endovascular therapy in peripheral artery disease: A prospective pilot study.

Magnetic resonance imaging·2026
Same journal

Reconstruction of MRI from undersampled k-spaces of double-contrast volume acquisitions using deep neural networks.

Magnetic resonance imaging·2026
Same journal

Radiofrequency-induced heating safety of brain MRI scans at 7 T in the presence of a shoulder implant.

Magnetic resonance imaging·2026
See all related articles

Short inversion time inversion recovery (STIR) MRI is effective for bone marrow imaging at 0.5 and 1.5 T. It excels in detecting red marrow lesions and osteomyelitis, though motion artifacts can be a limitation.

Area of Science:

  • Radiology
  • Medical Imaging
  • Magnetic Resonance Imaging

Background:

  • Bone marrow imaging is crucial for diagnosing various pathologies, including oncological conditions and infections.
  • Magnetic Resonance Imaging (MRI) offers detailed soft tissue contrast, but optimal sequences for bone marrow evaluation are continuously explored.
  • Short inversion time inversion recovery (STIR) is a pulse sequence known for its fat suppression capabilities.

Purpose of the Study:

  • To retrospectively evaluate the diagnostic utility of short inversion time inversion recovery (STIR) MRI sequences for bone marrow imaging.
  • To compare the contrast and image quality of STIR with other MRI sequences (spin-echo, gradient-echo) at 0.5 T and 1.5 T.
  • To assess the effectiveness of STIR in detecting various bone marrow lesions, particularly oncological and infectious etiologies.

Related Experiment Videos

Main Methods:

  • Retrospective analysis of MR images from 82 patients with diverse bone marrow lesions.
  • Comparison of STIR sequences against spin-echo (short TR/TE, long TR/TE) and gradient-echo sequences.
  • Optimization of pulse sequences for image quality, contrast, and fat nulling at 0.5 T and 1.5 T.

Main Results:

  • STIR demonstrated superior contrast for evaluating red marrow abnormalities (e.g., spine) compared to gradient-echo and T1-weighted images.
  • STIR imaging showed high sensitivity for detecting osteomyelitis, including soft tissue involvement.
  • Limitations included motion artifacts, particularly at 1.5 T, necessitating motion compensation, and potential overstatement of lesion margins due to water content sensitivity.

Conclusions:

  • Short inversion time inversion recovery (STIR) is a highly effective MRI pulse sequence for evaluating bone marrow abnormalities at both 0.5 T and 1.5 T.
  • STIR is particularly valuable for assessing red marrow pathologies and osteomyelitis.
  • Awareness of STIR's limitations, such as motion artifacts and margin overstatement, is essential for accurate interpretation.