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Updated: Aug 20, 2026
Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Moderate to severe obstructive sleep apnoea patients is associated with a higher incidence of visual field defect
C S L Tsang1, S L Chong, C K Ho
1Department of Ophthalmology, Tuen Mun Hospital, Hong Kong SAR, China. colette_tsg@hotmail.com
Purpose:
To compare the visual fields (VFs) and optic nerve head changes between obstructive sleep apnoea (OSA) in normotensive patients and an age-matched non-OSA population.
Design:
Case-control study.
Participants:
A total of 41 ethnic Chinese patients diagnosed with moderate to severe OSA referred from the Sleep Laboratory, ENT Department, Tuen Mun Hospital. A total of 35 age-matched non-OSA subjects recruited from the Ophthalmology Department, North District Hospital.
Methods:
Comprehensive ophthalmological and systemic history, complete ophthalmological examination, including central-30 computerized perimetry for all studied patients.
Main Outcome Measures:
Polysomnographic data, VF indices, optic disc changes.
Results:
In the OSA arm, VF indices were significantly subnormal and the incidence of suspicious glaucomatous disc changes was four times higher than that of the control arm. None of the studied patients suffered from any form of anterior segment complications.
Conclusions:
Moderate to severe OSA is associated with a higher incidence of VF defect and glaucomatous optic nerve changes.
