Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The cellular basis of traumatic bleeding.

Maureane Hoffman1

  • 1Department of Pathology, Duke University Medical Center, Durham, NC, USA.

Military Medicine
|January 18, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The kinetics and interplay of thrombin inhibition by 4 plasma proteinase inhibitors.

Blood vessels, thrombosis & hemostasis·2025
Same author

True anticoagulation safety cannot be achieved without better anticoagulants.

BMJ open quality·2025
Same author

Recombinant factor VIIa: new insights into the mechanism of action through product innovation.

Research and practice in thrombosis and haemostasis·2025
Same author

Modelling the effects of 4-factor prothrombin complex concentrate for the management of factor Xa-associated bleeding.

PloS one·2024
Same author

Ultrasoft platelet-like particles stop bleeding in rodent and porcine models of trauma.

Science translational medicine·2024
Same author

Emicizumab promotes factor Xa generation on endothelial cells.

Journal of thrombosis and haemostasis : JTH·2024

Hemorrhage is a major cause of death in trauma patients, especially in combat. While initial screening is adequate for military personnel, new hemostatic agents will require improved laboratory monitoring for effective treatment.

Area of Science:

  • Trauma and Emergency Medicine
  • Hematology
  • Military Medicine

Background:

  • Hemorrhage is a leading cause of death in trauma, necessitating effective management strategies.
  • Microvascular bleeding due to coagulopathy requires a different approach than surgical repair of major vessel transection.
  • Combat casualties present unique challenges in trauma care, including delayed medical attention and different injury patterns.

Purpose of the Study:

  • To summarize hemostasis monitoring in combat trauma patients.
  • To review the unique aspects of combat casualties and their medical treatment system.
  • To discuss findings from civilian studies relevant to combat trauma.

Main Methods:

  • Review of existing literature on trauma-induced coagulopathy and hemostasis monitoring.

Related Experiment Videos

  • Comparison of civilian trauma care with combat medical management.
  • Analysis of the challenges in providing timely care to combat casualties.

    • Main Results:

    • Routine screening is adequate for initial blood product administration in young, healthy military populations.
    • Coagulopathy development is infrequent in this demographic.
    • New hemostatic agents will necessitate enhanced laboratory monitoring.

    Conclusions:

    • Effective management of posttraumatic microvascular bleeding is crucial.
    • Understanding the differences between civilian and combat trauma care is essential.
    • Military medical personnel need to be aware of rapid hemorrhage control options in combat settings.