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Related Experiment Videos

Orbital exenteration: one size does not fit all.

Guy J Ben Simon1, Robert M Schwarcz, Raymond Douglas

  • 1Jules Stein Eye Institute and Department of Ophthalmology, David Geffen School of Medicine at UCLA, Los Angeles, California 90095-7006, USA. simon@jsei.ucla.edu

American Journal of Ophthalmology
|January 18, 2005
PubMed
Summary

Orbital exenteration indications are consistent over time. While curative for some cancers, outcomes depend on tumor type, and most patients opt for an eye patch post-surgery.

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Area of Science:

  • Ophthalmology
  • Surgical Oncology
  • Reconstructive Surgery

Background:

  • Orbital exenteration is a radical surgical procedure involving the removal of orbital contents.
  • Understanding clinical indications and outcomes is crucial for managing advanced orbital malignancies.
  • Previous data provide a benchmark for evaluating current practices and patient results.

Purpose of the Study:

  • To assess the current clinical indications for orbital exenteration at a tertiary referral center.
  • To compare clinicopathologic correlations and cosmetic outcomes with historical data.
  • To evaluate patient preferences for post-operative management, specifically eye patching.

Main Methods:

  • Retrospective, nonrandomized, consecutive case series.

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  • Data collected from January 1999 to December 2003 via Electronic Medical Record system.
  • Key outcomes included surgery type, histological margin status, survival, and eye patch use.

    • Main Results:

    • Thirty-four patients (mean age 67) underwent orbital exenteration for various orbital, ocular, and adnexal malignancies.
    • Squamous and basal cell carcinoma were the most frequent diagnoses.
    • Clear margins achieved in 68% of cases; most patients preferred an eye patch post-operatively.

    Conclusions:

    • Clinical indications for orbital exenteration have remained largely unchanged over four decades.
    • Orbital exenteration is curative for basal/squamous cell carcinoma but less effective for infiltrative tumors.
    • Patient preference for an eye patch is common, irrespective of reconstructive efforts.