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Published on: October 31, 2025
[Treatment strategies for neonatal pulmonary morbidity in Europe]
L Desnoulez1, J Empana, M Anceschi
1Service de médecine néonatale, hôpital Jeanne-de-Flandre, 59037 Lille, France. l-desnoulez@chru-lille.fr <l-desnoulez@chru-lille.fr>
Insights
This survey of European neonatal units found antenatal steroid and surfactant use aligned with recommendations for very preterm newborns. However, postnatal steroid utilization practices require further clarification.
Area of Science:
- Neonatal Medicine
- Pediatric Pulmonology
- Clinical Practice Surveys
Context:
- Pulmonary morbidity significantly impacts outcomes for very preterm infants.
- Variations in clinical practices can influence infant health.
- A comprehensive understanding of current treatment strategies is essential.
Purpose:
- To survey current practices in 14 European countries regarding the prevention and treatment of pulmonary morbidity in very preterm newborns.
- To describe strategies employed for managing respiratory complications in this vulnerable population.
- To compare surveyed practices with evidence-based recommendations.
Summary:
- A survey of neonatal units across 14 European countries was conducted using questionnaires on prenatal steroids, surfactant, and postnatal steroids.
- Results indicate that antenatal steroid administration and surfactant prescription generally adhere to recommended guidelines.
- Utilization patterns for postnatal steroids were found to be less clearly defined in the surveyed units.
Impact:
- Identifies adherence to best practices for antenatal steroids and surfactant in very preterm infants.
- Highlights areas of suboptimal or unclear practice regarding postnatal steroid use.
- Provides a benchmark for evaluating and improving respiratory care strategies for extremely premature neonates.
Objectives:
To survey practices in 14 European countries and to describe strategies for the prevention and treatment of pulmonary morbidity in very preterm newborns.
Methods:
Questionnaires covering the use of prenatal steroids, surfactant and postnatal steroids were sent in 1999-2000 to every neonatal unit taking very preterm newborns in charge in population-based areas covering at least 20,000 births annually. One questionnaire was sent by surveyed unit.
Results:
Results are given concerning these three treatments and compared to evidence based recommendations.
Conclusion:
Antenatal steroids were given at recommended terms. Surfactant was prescribed with respect of best practices. Postnatal steroids utilisation was not well described.
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