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Updated: Aug 20, 2026

Retroperitoneal Laparoscopic Debridement and Drainage for Pancreatic Abscess
Published on: March 15, 2024
Pancreatic abscess secondary to Alcaligenes faecalis
Mahi Lakshmi Ashwath1, Harold P Katner
1Department of Internal Medicine, Mercer University School of Medicine, Macon, Georgia, USA. Mahi_Lakshmi@yahoo.com
Abstract:
We report a patient with pancreatic abscesses and necrosis secondary to Alcaligenes faecalis infection. He initially presented with alcohol-induced acute pancreatitis. Twenty days after the initial presentation, he re-presented with increasing pain and was found to have pancreatic necrosis and abscesses. Treatment was initiated with meropenem. Because of persistent fevers, computed tomography-guided drainage was performed. The fluid grew A faecalis resistant to meropenem and the patient continued to be febrile. He recovered only after adequate surgical intervention and appropriate antibiotic coverage. Although this is the first case of A faecalis reported to cause pancreatic abscess, we believe selection of this organism occurred because surgical drainage was delayed while the patient was on the recommended treatment with meropenem. This case emphasizes the need for early surgical drainage of pancreatic abscesses to avoid the selection of such resistant pathogens.
Insights
A rare Alcaligenes faecalis infection led to pancreatic abscesses and necrosis in a patient with acute pancreatitis. Early surgical drainage is crucial to prevent the selection of resistant pathogens like A. faecalis.
Area of Science:
- Infectious Diseases
- Gastroenterology
- Surgical Pathology
Background:
- Alcohol-induced acute pancreatitis can lead to severe complications.
- Pancreatic necrosis and abscess formation are serious sequelae requiring prompt management.
Observation:
- A patient with alcohol-induced acute pancreatitis developed secondary pancreatic necrosis and abscesses.
- The abscess fluid culture revealed Alcaligenes faecalis, a pathogen resistant to meropenem.
- Initial treatment with meropenem and delayed surgical drainage contributed to persistent fever and pathogen resistance.
Findings:
- Alcaligenes faecalis can cause pancreatic abscesses, particularly in cases with delayed surgical intervention.
- Meropenem resistance in A. faecalis was observed, necessitating alternative treatment strategies.
- Successful recovery was achieved only after surgical intervention and appropriate antibiotic therapy.
Implications:
- This case highlights the critical importance of early surgical drainage for pancreatic abscesses.
- Delayed intervention can promote the selection of multidrug-resistant organisms.
- Clinicians should consider early surgical consultation and intervention in managing complex pancreatic infections.
Related Concept Videos
Acute Pancreatitis II: Pathophysiology
Acute Pancreatitis II: Clinical Manifestations and Management
Chronic Pancreatitis II: Pathophysiology
Acute Pancreatitis I: Introduction
Acute Pancreatitis I: Introduction
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
Chronic Pancreatitis I: Introduction