Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Motion sickness.

John F Golding1, Michael A Gresty

  • 1Department of Psychology, University of Westminster, London, UK.

Current Opinion in Neurology
|January 19, 2005
PubMed
Summary
This summary is machine-generated.

New research identifies specific vehicle motion characteristics that cause sickness, aiding engineering design and passenger advice. Behavioral and potential drug interventions show promise for motion sickness relief.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Development and Initial Validation of the Quality of life Evaluation in <i>NF2</i> -related Schwannomatosis Trials (QUEST) Assessment.

medRxiv : the preprint server for health sciences·2026
Same author

New therapies to treat nausea and vomiting: clinical need, progress towards novelty and research challenges.

Expert review of clinical pharmacology·2026
Same author

Congenital nystagmus mitigates against motion sickness.

Journal of neurology, neurosurgery, and psychiatry·2026
Same author

German Translation and Validation of the Visually Induced Motion Sickness Susceptibility Questionnaire Short (VIMSSQ-short).

Multisensory research·2025
Same author

Sensitization of Visually Induced Motion Sickness by Prior Provocative Physical Motion.

Aerospace medicine and human performance·2024
Same author

Treating benign paroxysmal positional vertigo in acute traumatic brain injury: a prospective, randomised clinical trial assessing safety, feasibility, and efficacy.

BMJ neurology open·2024
Same journal

Movement disorders and Parkinson's disease: collaborative and interdisciplinary research to advance understanding of neural circuit dysfunction, pathophysiology, and care: new horizons in technology, neuroimaging, neurophysiology, and genetics toward personalized medicine.

Current opinion in neurology·2026
Same journal

Editorial introduction.

Current opinion in neurology·2026
Same journal

Multimodal mapping of balance dysfunction in Parkinson's disease: a consensus roadmap for research and intervention.

Current opinion in neurology·2026
Same journal

Tourette syndrome: brain neurophysiology, circuit dysfunction, and neuromodulation across invasive and noninvasive approaches.

Current opinion in neurology·2026
Same journal

Dystonia: from phenotypes to genetics and therapeutic advances.

Current opinion in neurology·2026
Same journal

What can we learn from eye movements in movement disorders and Parkinson's disease?

Current opinion in neurology·2026
See all related articles

Area of Science:

  • Neuroscience
  • Biomechanics
  • Human Factors Engineering

Background:

  • Motion sickness is a prevalent issue exacerbated by new technologies like tilting trains and virtual reality.
  • Previous understanding of motion sickness triggers was limited, hindering effective prevention and treatment.

Purpose of the Study:

  • To precisely identify the mechanical and frequency characteristics of motion that provoke sickness.
  • To explore and evaluate behavioral and pharmacological interventions for motion sickness suppression.

Main Methods:

  • Analysis of vehicle ride characteristics and motion frequency.
  • Investigation of perceptual shifts, reflex eye movements, and vestibular system responses.
  • Evaluation of behavioral countermeasures (e.g., controlled breathing) and potential pharmacological agents.

Related Experiment Videos

Main Results:

  • Precise identification of nauseogenic mechanical ride characteristics, informing future vehicle design.
  • Defined frequency characteristics of motion sickness triggers, linked to altered perception and reflex eye movements.
  • Vestibular 'velocity store' time constant modification identified as a potential habituation marker.
  • Behavioral interventions like controlled breathing demonstrate significant nausea amelioration.
  • Promising results from N-methyl-D-aspartate antagonists and 5HT1a receptor agonists in animal models.

Conclusions:

  • Engineering guidelines for vehicle design, particularly suspension systems, can be developed based on identified motion triggers.
  • Recommendations for at-risk passengers can be formulated.
  • Behavioral countermeasures offer practical, short-term relief for motion sickness.
  • Further human trials are needed for novel pharmacological interventions to confirm efficacy and safety.