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Fifth ventricle: an unusual cystic lesion of the conus medullaris
G Liccardo1, F Ruggeri, L De Cerchio
1Neurosurgery, Department of Neuroscience, University of Rome Tor Vergata, 81-00133 Rome, Italy.
Study Design:
Cystic dilatation of the fifth ventricle on its own is an extremely rare pathological event in adults whose pathogenesis is uncertain. The authors describe a personal case of 'fifth ventricle' and review the pertinent literature.
Objective:
To emphasize the importance of including the fifth ventricle in differential diagnosis of lesions of the conus medullaris to ensure proper treatment.
Setting:
Italy.
Methods:
A 30-year-old woman was referred to us for recurrent low back pain. The patient was assessed by clinical, electrophysiological (motor evoked potential, somatosensorial evoked potential and electromyography of the perineal and lower limb muscles) and urodynamic investigations as well as a magnetic resonance imaging (MRI) of the lumbar-sacral segment with and without gadolinium enhancement, subsequently extended to the entire vertebral column and brain. Follow-up consisted of periodic clinical evaluation and lumbar-sacral MRI after 1 and 2 years.
Results:
General physical examination, electrophysiological and urodynamic investigations were all negative, confirming the subjective nature of the patient's symptoms. Lumbar-sacral MRI demonstrated the presence of a cyst lesion containing cerebrospinal fluid (CSF), which did not enhance after gadolinium, compatible with the diagnosis of the terminal ventricle. By extending the MRI investigation to the entire vertebral column and brain, it was possible to exclude an association with other malformations of the central nervous system. Clinical and radiological follow-up confirmed the nonevolutive nature of the lesion 1 and 2 years later.
Conclusions:
The lack of clinical symptoms and the stability of the radiological situation at 1 and 2 years follow-up motivated our choice of conservative treatment.
Insights
A rare cystic dilatation of the fifth ventricle was identified in a patient with low back pain. This finding, confirmed by MRI, was stable over two years, leading to conservative management.
Area of Science:
- Neurology
- Radiology
- Neuroanatomy
Background:
- Cystic dilatation of the fifth ventricle is an exceptionally rare condition in adults with an unclear pathogenesis.
- The fifth ventricle, also known as the terminal ventricle, is a midline cerebrospinal fluid (CSF)-filled space.
- This case highlights a unique presentation of this rare entity.
Observation:
- A 30-year-old woman presented with recurrent low back pain.
- Comprehensive clinical, electrophysiological, and urodynamic assessments were unremarkable.
- Magnetic Resonance Imaging (MRI) revealed a cyst in the lumbar-sacral region, consistent with a terminal ventricle, with no associated central nervous system malformations.
Findings:
- The cyst was confirmed to be CSF-filled and did not enhance with gadolinium.
- Serial MRI scans over two years showed no evolution of the lesion.
- The patient's symptoms were deemed subjective, with no objective neurological deficits.
Implications:
- The terminal ventricle should be considered in the differential diagnosis of conus medullaris lesions.
- Conservative management is appropriate for stable, asymptomatic or subjectively symptomatic fifth ventricle cysts.
- This case contributes to the understanding of rare cystic dilatations within the central nervous system.
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