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[Microbiological findings in children with an indwelling central venous catheter]
Martin Uher1, Mária Pisarcíková, Milan Kurák
1Department of Pediatrics, St. Cyril and Method's Hospital, Bratislava, Slovak Republic. uhermar@hotmail.com
Insights
Central venous catheters (CVCs) in children can lead to infections. Minimizing CVC sampling and maintaining strict sterile techniques during insertion and use are crucial for reducing infectious complications and improving patient outcomes.
Area of Science:
- Pediatric Infectious Diseases
- Medical Microbiology
- Catheter-Associated Infections
Background:
- Central venous catheters (CVCs) offer patient benefits but pose risks of infectious complications.
- A 5-year microbiological evaluation of pediatric patients with indwelling CVCs was conducted.
Purpose of the Study:
- To perform a microbiological evaluation of pediatric patients with indwelling CVCs over a 5-year period.
- To assess the incidence and types of infectious complications associated with CVC use in children.
Main Methods:
- A retrospective analysis of 218 CVCs in 165 pediatric patients over 5 years (1995-1999).
- Microbiological assessment of blood and catheter tips using standard sterile techniques and culture systems.
- Infectious complication diagnosis based on Sirges-Serra classification and CDC criteria.
Main Results:
- 71 infectious complications were observed, including 31 contaminated catheters, 27 catheter sepsis cases, and 11 catheter bacteremia cases.
- Staphylococcus epidermidis and Candida spp. were the dominant microbes. Gram-negative bacteria predominated in catheter sepsis.
- No infectious complications occurred in 67.43% of catheters. CVCs were implicated as the cause of death in 3.6% of patients.
Conclusions:
- Microbiological findings align with existing literature.
- Minimizing CVC sampling is essential for reducing infectious complication rates.
- Strict sterile insertion and aseptic handling of CVCs are critical for minimizing infection risk.
Introduction:
Besides their obvious advantages for the patient, central venous catheters (CVC) also carry the risk of possible infectious complications. The purpose of our investigation was to carry out a microbiological evaluation of a 5-year set of paediatric patients with indwelling CVCs.
Patients And Methods:
In the group were 218 CVCs inserted to 165 children over a period of 5 years. There were 26 multi-lumen catheters (11.927 %) and 192 single-lumen catheters (88.073 %). The mean indwelling period was 10.1 days per 1 CVC. Blood for microbiology was removed by a physician from the CVC after disinfecting its opening under standard sterile conditions into a commercial sampling vessel HEMOD (Imuna, Sarisske Michalany, Slovak Republic) or into a vessel of an automated haemoculture system BactecPeds PLUS/F (Becton Dickinson and Comp., Spark,MA, USA). When removing the tip of the CVC we disinfected, before removing the CVC, the area around the insertion with isopropyl or ethyl alcohol. We released the fixed CVC and 1 minute after disinfection we pulled out the CVC and cut off the end or rather the tip of the catheter (approx. 1-3 cm of the tip) into a sterile test tube. To establish the diagnosis of infectious complications we used the 1995 Sirges-Serra classification and the CDC criteria.
Results:
In 5 years (1995-1999) we had 71 infectious complications. There were 31 contaminated catheters, 27 cases of catheter sepsis and 11 cases of catheter bacteraemia. With 147 catheters (67.43%) there were no infectious complications. Dominant microbes were Staphylococcus epidermidis (32 cases - 11 from haemocultures and 21 from CVCs) and Candida spp. (30 cases, 17 from haemocultures and 13 from CVCs). Among the microbiological agents of catheter sepsis predominated Gram-negative bacteria. Out of the whole analysed group 41 children (24.8 %) died. CVC as the cause of death was demonstrated in 6 children (3.636 % of patients with CVC).
Conclusions:
Microbiological findings in our group are in line with literary data. To reduce the incidence of infectious complications it is important to limit sampling from CVC to a minimum. Insertion of CVCs under strict sterile conditions and aseptic handling of all entries into the central bloodstream reduces to a minimum the risk of infectious complications.
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