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Health status of Indian population--current scenario

Tester F Ashavaid1, Seema P Todur, Alpa J Dherai

  • 1Department of Biochemsitry, P. D. Hinduja National Hospital and Medical Research Centre, Veer Savarkar Marg, Mahim, Mumbai. dr_tashavaid@hindujahospital.com

The Journal of the Association of Physicians of India
|January 20, 2005
PubMed

Insights

Establishing reference intervals for biochemical and hematological analytes is crucial. This study found high prevalence of hypertension and diabetes, highlighting the need for lifestyle changes to reduce coronary artery disease (CAD) risk.

Area of Science:

  • Clinical Biochemistry
  • Hematology
  • Epidemiology

Background:

  • Establishing population-specific reference intervals for biochemical and hematological analytes is essential for accurate health assessments.
  • Coronary Artery Disease (CAD) prevalence and associated risk factors require ongoing investigation within diverse populations.

Purpose of the Study:

  • To establish reference intervals for biochemical and hematological analytes in a healthy population.
  • To determine the prevalence of CAD and identify associated risk factors in a large cohort undergoing health check-ups.

Main Methods:

  • Manual screening of medical records for 39,940 subjects from 1996-2001.
  • Utilizing SPSS-8.0 for statistical analysis, including percentile calculations and 90% confidence intervals (CI).

Main Results:

  • Prevalence rates: Hypertension (22.5%), Diabetes Mellitus (14.2%), and Coronary Artery Disease (CAD) (3.9%).
  • Only 41.1% of the population was normolipemic; reference intervals for lipids may require adjustment, potentially reclassifying individuals at higher CAD risk.
  • Most analytes aligned with existing reference values, with no observed influence of diet on these intervals.

Conclusions:

  • Adjusting lipid reference intervals presents a clinical dilemma, potentially impacting CAD risk assessment.
  • Lifestyle and dietary modifications are critical interventions to mitigate the public health burden of CAD in this population.
Abstract

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