Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Chronic myeloid leukemia.

N Singhal1, P P Bapsy, K G Babu

  • 1Department of Medical Oncology, Kidwai Memorial Institute of Oncology, Bangalore.

The Journal of the Association of Physicians of India
|January 20, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Search for Dark Matter and Supersymmetry with a Compressed Mass Spectrum in the Vector Boson Fusion Topology in Proton-Proton Collisions at sqrt[s]=8  TeV.

Physical review letters·2017
Same author

Dietary Supplement Use in Older People Attending Memory Clinics in Australia.

The journal of nutrition, health & aging·2016
Same author

Combined surgical and immunosupressive therapy for encapsulating peritoneal sclerosis.

Indian journal of nephrology·2016
Same author

Medical morbidity and mortality conferences: past, present and future.

Postgraduate medical journal·2016
Same author

Profile of diabetes in men aged 79-97 years: the Western Australian Health in Men Study.

Diabetic medicine : a journal of the British Diabetic Association·2016
Same author

Fibrosis is not just fibrosis - basement membrane modelling and collagen metabolism differs between hepatitis B- and C-induced injury.

Alimentary pharmacology & therapeutics·2016
Same journal

Indian Expert Consensus on Allergic Rhinitis in Women: A Modified Delphi Survey.

The Journal of the Association of Physicians of India·2026
Same journal

Systematic Review of Topical Capsaicin 0.075% for the Treatment of Neuropathic Pain: Efficacy, Safety, and Tolerability.

The Journal of the Association of Physicians of India·2026
Same journal

Sodium-Glucose Cotransporter 2 Inhibitors in Kidney Diseases Other Than That Due to Diabetes: Benefits in Composite Renal Outcomes Driven by Immunoglobulin A Nephropathy.

The Journal of the Association of Physicians of India·2026
Same journal

<i>Fasciolopsis buski</i> Diagnosed by Upper Gastrointestinal Endoscopy.

The Journal of the Association of Physicians of India·2026
Same journal

"Academic Overdose" among Healthcare Professionals.

The Journal of the Association of Physicians of India·2026
Same journal

Respiratory Examination for Postgraduate Residents: Unrevealing Expert's Questions and Answers.

The Journal of the Association of Physicians of India·2026
See all related articles

Chronic myeloid leukemia (CML) treatment options are reviewed, including stem cell transplant, chemotherapy, and targeted therapy. Imatinib shows promising results as a new standard of care for CML.

Area of Science:

  • Hematology
  • Oncology
  • Molecular Biology

Background:

  • Chronic myeloid leukemia (CML) is a common hematological malignancy.
  • CML results from abnormal bcr-abl tyrosine kinase activity due to the Philadelphia chromosome.
  • This leads to uncontrolled proliferation of myeloid cells.

Purpose of the Study:

  • To discuss current and emerging treatment options for chronic myeloid leukemia.
  • To evaluate the efficacy and role of different therapeutic strategies.
  • To highlight the significance of targeted therapy in CML management.

Main Methods:

  • Review of existing literature on CML treatments.
  • Analysis of clinical outcomes for various therapeutic modalities.
  • Comparison of traditional therapies with novel targeted agents.

Related Experiment Videos

Main Results:

  • Allogeneic stem cell transplant is the only curative option for CML.
  • Hydroxyurea and Busulfan control leukocyte count but not survival.
  • Interferon-based therapies offer functional cure in some patients.
  • Imatinib, a targeted oral therapy, demonstrates promising early results.

Conclusions:

  • Imatinib represents a significant advancement in CML treatment.
  • Targeted therapy with imatinib is considered a new standard of care for CML.
  • Further research is ongoing to optimize CML management strategies.