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Updated: Aug 20, 2026

Quantitative Fundus Autofluorescence for the Evaluation of Retinal Diseases
07:22

Quantitative Fundus Autofluorescence for the Evaluation of Retinal Diseases

Published on: March 11, 2016

[The adverse reactions and treatment of fundus fluorescein angiography]

Guiying Mai1, Hong Yan, Mei Li

  • 1Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China.

Yan Ke Xue Bao = Eye Science
|January 20, 2005
PubMed
Abstract

Insights

Fluorescein angiography (FA) is generally safe for examining fundus diseases, with most adverse events being mild. Severe reactions are rare and treatable, with no deaths reported in this study.

Area of Science:

  • Ophthalmology
  • Medical Imaging

Context:

  • Fluorescein angiography (FA) is a key diagnostic tool for various fundus diseases.
  • Assessing the safety profile of FA is crucial for clinical practice.

Purpose:

  • To investigate the safety of fluorescein angiography.
  • To evaluate the examination's adverse event rate and management protocols.

Summary:

  • A retrospective analysis of 8,344 patients undergoing FA revealed an 8.3% adverse event rate.
  • Mild to moderate events (7.87%) required minimal intervention, while severe events (0.35%) were successfully managed with treatment, and no deaths occurred.

Impact:

  • This study confirms fluorescein angiography's general safety for fundus examination.
  • Highlights the importance of patient assessment, understanding indications/contraindications, and preparedness for emergent events.

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