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Updated: Aug 5, 2026

An In Ovo Model for Testing Insulin-mimetic Compounds
Published on: April 23, 2018
Insulin detemir--a new basal insulin analog
Jennifer D Goldman-Levine1, Karen W Lee
1Department of Pharmacy Practice, School of Pharmacy-Boston, Massachusetts College of Pharmacy and Health Sciences, 179 Longwood Avenue, Boston, MA 02115-5804, USA. jgoldman-levine@bos.mcphs.edu
Objective:
To review the pharmacology, pharmacokinetics, clinical trial data, adverse effects, and role in therapy of insulin detemir.
Data Sources:
Articles and meeting abstracts were identified through searches of MEDLINE (1996-June 2004), EMBASE (1980-June 2004), and International Pharmaceutical Abstracts (1970-June 2004) databases, and unpublished information was provided by the manufacturer.
Study Selection And Data Extraction:
All available studies relating to insulin detemir's pharmacology were selected. Only human studies were used for pharmacokinetic, drug interaction, efficacy, and safety data.
Data Synthesis:
Insulin detemir is a basal insulin analog that has been shown to improve glycemic control in patients with type 1 and type 2 diabetes.
Conclusions:
Insulin detemir offers some benefits over NPH for use as basal insulin in patients with type 1 and type 2 diabetes.
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