Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Invasive epithelial mesothelioma in a dog.

F Reggeti1, B Brisson, K Ruotsalo

  • 1Department of Pathobiology, University of Guelph, Guelph, Ontario N1G 2W1, Canada. freggeti@uoguelph.ca

Veterinary Pathology
|January 20, 2005
PubMed
Summary

This study details an invasive epithelial mesothelioma in a Golden Retriever, highlighting its widespread involvement and malignant cellular features. Immunohistochemistry confirmed neoplastic cells coexpressing vimentin and cytokeratin, aiding diagnosis.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Increased serum amyloid A and urinary kidney injury marker-1 concentrations in cats with pyelonephritis: a diagnostic accuracy study.

The Journal of small animal practice·2026
Same author

Accuracy of a point-of-care major crossmatch test and risk factors for major crossmatch incompatibility in cats.

Veterinary journal (London, England : 1997)·2021
Same author

Technical note: Assessment of neutrophil endocytosis and proteolytic degradation and its relationship with phagocytosis and oxidative burst in dairy cows.

Journal of dairy science·2019
Same author

Expression of Kidney Injury Molecule-1 in Healthy and Diseased Feline Kidney Tissue.

Veterinary pathology·2017
Same author

Patent ductus arteriosus in cats (Felis catus): 50 cases (2000-2015).

Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology·2016
Same author

Characterization of kidney injury molecule-1 in cats.

Journal of veterinary internal medicine·2014

Area of Science:

  • Veterinary Pathology
  • Oncology
  • Canine Neoplasia

Background:

  • Mesothelioma is a rare but aggressive tumor arising from mesothelial cells lining body cavities.
  • Epithelial mesothelioma presents a diagnostic challenge, particularly in veterinary medicine.
  • Accurate characterization is crucial for prognosis and treatment strategies in affected animals.

Observation:

  • A case of invasive epithelial mesothelioma in an 11-year-old male Golden Retriever is presented.
  • The tumor extensively involved the pericardium, pleura, mediastinum, and peritoneum, with submesothelial tissue invasion.
  • Thoracic fluid analysis revealed neoplastic cells with malignant characteristics amidst inflammatory cells and erythrocytes.

Findings:

  • Histological examination showed nests of epithelioid cells with high mitotic activity and multinucleation infiltrating tissues.

Related Experiment Videos

  • Immunohistochemical staining demonstrated strong coexpression of vimentin and cytokeratin in neoplastic cells.
  • These markers were essential for differentiating the mesothelioma from other nonmesothelial epithelial tumors.

    • Implications:

    • This case contributes to the understanding of mesothelioma presentation and behavior in canine patients.
    • The immunohistochemical profile provides valuable diagnostic criteria for veterinary pathologists.
    • Accurate diagnosis of canine mesothelioma impacts clinical management and research into similar human cancers.