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Rapid Generation of Amyloid from Native Proteins In vitro
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Protein amyloidose misfolding: mechanisms, detection, and pathological implications

Nigil Satish Jeyashekar1, Ajit Sadana, Tuan Vo-Dinh

  • 1Chemical Engineering Department, University of Mississippi, Oak Ridge, TN, USA.

Methods in Molecular Biology (Clifton, N.J.)
|January 20, 2005
PubMed
Summary

Misfolded proteins form amyloid fibrils, causing fatal amyloidosis diseases. Despite diverse origins, amyloid fibrils share structural similarities, enabling the development of universal therapeutic strategies to combat these protein misfolding diseases.

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