Detection of IgA anti-Entamoeba histolytica in the patients' saliva

E. histolytica is a protozoan parasite with worldwide distribution. The diagnosis of this parasite still depends on the microscopic examination. Determination of the sIgA in the different body fluid proves to be of diagnostic value in many pathogens. To find out the potentials of salivary sIgA in diagnosis of intestinal amoebiasis, 30 patients with parasitologic proved E. histolytica and 30 cross-matched negative controls were selected for levels of salivary sIgA using radial immunodiffuion technique. The result showed a high significant increase in the mean concentration of salivary sIgA in patients rather controls. However, six negative controls gave positive sIgA. So, salivary IgA concentration has a predictive diagnostic values of intestinal amoebiasis, when the stool examination is practically impossible as well as in tissue amoebiasis.