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Updated: Aug 20, 2026

Surgical Training for the Implantation of Neocortical Microelectrode Arrays Using a Formaldehyde-fixed Human Cadaver Model
Published on: November 19, 2017
Preservation of cadavers for surgical technique training
Rosane Maria Guimarães da Silva1, Julia Maria Matera, Antonio Augusto Coppi Maciel Ribeiro
1Department of Surgery, Faculty of Veterinary Medicine, University of São Paulo, Brazil. materajm@usp.br
Objective:
To evaluate a technique for preservation of organoleptic tissue characteristics (color, odor, texture, and flexibility) in cadavers used for surgical instruction.
Study Design:
Experimental study.
Animals:
Forty-three canine cadavers.
Methods:
Cadavers were preserved with a modified Larssen solution of the Hospital Cochim, Paris and cryopreservation. Tissue handling qualities were evaluated in surgical laboratory sessions.
Results:
All cadavers kept texture and tissues consistency, especially skin and muscle, similar to those of live animals. Some skin desquamation and pallor of the mucous membranes occurred with repetitive freeze-thaw cycles.
Conclusions:
This preservation technique provides acceptable cadaver quality and tissue handling for use in surgical instruction.
Clinical Relevance:
Preparation of patient cadavers by intravascular injection of modified Larssen solution yielded suitable instructional models for surgical training.
