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Updated: Aug 20, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
Multiple avascular necrosis in a patient with systemic lupus erythematosus/systemic sclerosis overlap syndrome
Javier Alberto Cavallasca1, Hugo Armando Laborde, Mariela Beatriz Araujo
1Division of Rheumatology, Hospital de Clinicas José de San Martín, Faculty of Medicine, University of Buenos Aires, Argentina. pravier@hotmail.com
Abstract:
A white female patient developed overlapping features of systemic lupus erythematosus (SLE) and systemic sclerosis (SSc) with severe pulmonary compromise. She was treated with steroids and azathioprine, which improved her clinical condition and spirometric status. In May 2002 she presented with continuous pain in her left ankle that continued even during rest and under treatment with nonsteroidal anti-inflammatory drugs (NSAIDs). Magnetic resonance imaging (MRI) showed multiple avascular necrosis (AVN). Rest and kinesitherapy were indicated for 1 year, and gradually an orthosis was introduced allowing the patient to walk normally.
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