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Diagnosis of Hirschsprung's Disease by Immunostaining Rectal Suction Biopsies for Calretinin, S100 Protein and Protein Gene Product 9.5
Published on: April 26, 2019
Long-term results of treatment of Hirschsprung's disease
Scott A Engum1, Jay L Grosfeld
1Section of Pediatric Surgery, Riley Children's Hospital, Indiana University Medical Center, 702 Barnhill Drive, Indianapolis, IN 46202, USA. sengum@iupui.edu
Insights
Hirschsprung
Area of Science:
- Pediatric Surgery
- Gastroenterology
- Clinical Outcomes
Background:
- Hirschsprung's disease (HD) affects the large intestine, requiring surgical intervention.
- While many children achieve good initial outcomes, long-term complications are a significant concern.
- Assessing long-term functional outcomes after surgical management presents challenges.
Purpose of the Study:
- To discuss the common long-term problems following surgical treatment for Hirschsprung's disease.
- To analyze the impact of these complications on patients' quality of life.
- To provide a comprehensive overview of post-surgical challenges in pediatric HD.
Main Methods:
- Review and synthesis of existing long-term follow-up studies on Hirschsprung's disease.
- Analysis of reported complications including constipation, incontinence, and enterocolitis.
- Discussion of the impact on lifestyle and quality of life.
Main Results:
- Constipation and incontinence are the most frequent long-term issues.
- Enterocolitis remains a serious, though less frequent, complication.
- The overall impact on a child's quality of life is a critical consideration.
Conclusions:
- Long-term management of Hirschsprung's disease requires addressing persistent functional issues.
- Continuous monitoring and support are essential for improving quality of life in affected children.
- Further research into optimizing long-term care strategies for Hirschsprung's disease is warranted.
Abstract:
Many children with Hirschsprung's disease (HD) have a good outcome following surgical treatment, but long-term follow-up studies have identified a number of concerns. Analysis of long-term function in children after surgical management is difficult. The most commonly encountered problems include constipation, incontinence, enterocolitis and the overall impact of the disease on lifestyle (quality of life). Other complications are less frequent. Each of these problems will be discussed.