Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Viable myocardium: how much is enough?

Holger P Salazar1, James V Talano

  • 1Department of Medicine, Section of Cardiology, Tulane University Health Sciences Center, New Orleans, LA 70112, USA.

Echocardiography (Mount Kisco, N.Y.)
|January 22, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Detection of pulmonary vein stenosis by transesophageal echocardiography: comparison with multidetector computed tomography.

American heart journal·2007
Same author

Usefulness of electron-beam computed tomography.

The American journal of cardiology·2002
See all related articles

Assessing myocardial viability using imaging helps identify patients with coronary artery disease (CAD) who benefit from revascularization. Restoring blood flow can improve heart function, reducing heart failure risks.

Area of Science:

  • Cardiology
  • Medical Imaging

Background:

  • Left ventricular systolic dysfunction often stems from coronary artery disease (CAD).
  • Chronic hypoperfusion in CAD alters cardiac myocyte metabolism, creating a perfusion-contraction mismatch where function is compromised for survival.
  • Timely revascularization can restore metabolism and cardiac function.

Purpose of the Study:

  • To review the significance of myocardial viability assessment in guiding revascularization decisions.
  • To determine the extent of viable myocardium necessary to warrant revascularization.
  • To highlight the link between improved myocardial function and reduced morbidity/mortality from heart failure and arrhythmias.

Main Methods:

  • Review of noninvasive imaging modalities for assessing myocardial viability.

Related Experiment Videos

  • Discussion of nuclear imaging techniques (e.g., thallium-201 SPECT, PET) and their sensitivity/specificity.
  • Evaluation of dobutamine stress echocardiogram (DSE) and contrast-enhanced MRI for viability assessment.

    • Main Results:

    • Noninvasive imaging effectively identifies myocardial viability, aiding patient selection for revascularization.
    • Nuclear imaging offers high sensitivity but lower specificity; DSE has lower sensitivity but better specificity.
    • Contrast-enhanced MRI is emerging as a sensitive and specific tool for viability assessment.

    Conclusions:

    • Accurate assessment of myocardial viability is crucial for optimizing revascularization strategies in CAD patients.
    • Identifying viable myocardium guides treatment, potentially improving outcomes and reducing heart failure complications.
    • Improved cardiac function post-revascularization correlates with decreased morbidity and mortality.