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Contact sensitization in 1094 children undergoing patch testing over a 7-year period
Stefania Seidenari1, Francesca Giusti, Patrizia Pepe
1Department of Dermatology, University of Modena and Reggio Emilia, Italy. seidenari.stefania@unimo.it
Pediatric Dermatology
|January 22, 2005
Summary
Periodic patch testing is crucial for children due to frequent contact sensitization. This study identified emerging allergens and updated pediatric testing series based on recent data, highlighting significant changes in sensitization rates over time.
Area of Science:
- Pediatric Dermatology
- Allergology
- Contact Dermatitis
Background:
- Contact sensitization is common in children.
- Exposure to sensitizing agents changes rapidly, necessitating regular evaluation of patch test results.
Purpose of the Study:
- To compare recent contact sensitization data in children (1995-2001) with previous findings (1988-1994).
- To identify emerging allergens and update the pediatric patch test series.
Main Methods:
- 1094 children were examined between 1995 and 2001.
- 997 patients underwent patch testing with a 30-allergen pediatric series; 97 were tested with 46 allergens.
- Allergic reactions were analyzed and compared to historical data.
Main Results:
- 52.1% of tested children showed positive results for allergies.
- The highest sensitization rate was observed in children under 3 years of age.
- Neomycin, nickel, wool alcohols, thimerosal, and ammoniated mercury were the most frequent allergens. Sensitization to these and other allergens like propolis, potassium dichromate, and thiuram mix increased compared to 1988-1995.
Conclusions:
- Sensitization rates to various allergens vary significantly over time.
- Periodic evaluation of patch test results in children is essential for updating diagnostic testing series.