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Updated: Aug 20, 2026

Intra-Peritoneal Transplantation for Generating Acute Myeloid Leukemia in Mice
Published on: January 6, 2023
Chronic myeloid leukemia following kidney transplantation
Luís Arthur Flores Pelloso1, Mireille Guimarães Vaz de Campos, Marília Nascimento
1Disciplina de Hematologia e Hemoterapia, UNIFESP-EPM, Rua Botucatu 740, 04023-900 São Paulo, SP Brazil.
Abstract:
Immunosuppressed renal recipients are at an increased risk of developing cancer. Leukemias are less frequent than other hematopoietic tumours and development of CML after immunosuppression is rare. We describe a 37-year-old male who presented with left-shifted leukocytosis, hypercellular bone marrow 32 months after the kidney transplant. G-banding karyotype revealed 46,XY,t(9;22)(q34;q11) and the diagnosis of chronic myeloid leukemia was made. This is the 13th case of CML after kidney transplant reported. Whether this CML appeared as a random phenomenon or chemically induced is a matter of debate. Some individuals might have an increased susceptibility to the effects of azathioprine.
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