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Ocular invasion in mucormycosis.

T A Sponsler1, J W Sassani, L N Johnson

  • 1Department of Ophthalmology, Milton S. Hershey Medical Center, Penn State University, Hershey.

Survey of Ophthalmology
|March 1, 1992
PubMed
Summary

Rhinocerebral mucormycosis invading the eye, a rare and fatal fungal infection, often spreads via posterior ciliary arteries. Ocular involvement in this condition signals a poor prognosis for patients.

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Area of Science:

  • Ophthalmology
  • Mycology
  • Pathology

Background:

  • Rhinocerebral mucormycosis is a severe fungal infection with high mortality.
  • Ocular invasion is a rare but devastating complication.

Observation:

  • Histopathology revealed fungal hyphae in the inner sclera.
  • Posterior ciliary arteries showed significant fungal involvement, suggesting arterial spread.

Findings:

  • This case, along with five previously reported, highlights the arterial route of fungal invasion to the eye.
  • All reported cases of ocular invasion in rhinocerebral mucormycosis resulted in patient death.

Implications:

  • Ocular fungal infiltration in rhinocerebral mucormycosis is a critical indicator of a poor prognosis.
  • Early detection and understanding of fungal spread mechanisms are crucial for managing this aggressive infection.

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