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Effect of wavelength on low-intensity laser irradiation-stimulated cell proliferation in vitro
Pete Moore1, Tisha D Ridgway, Russell G Higbee
1University of Oklahoma College of Dentistry, Oklahoma City, Oklahoma 73104, USA.
Background And Objectives:
There exist contradictory reports about low-intensity laser light-stimulated cell proliferation. The purpose of this study was to determine the effect of wavelength on proliferation of cultured murine cells.
Study Design/Materials And Methods:
Proliferation of primary cell cultures was measured after irradiation with varying laser wavelengths.
Results:
Fibroblasts proliferated faster than endothelial cells in response to laser irradiation. Maximum cell proliferation occurred with 665 and 675 nm light, whereas 810 nm light was inhibitory to fibroblasts.
Conclusions:
These observations suggest that both wavelength and cell type influence the cell proliferation response to low-intensity laser irradiation.
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