Related Experiment Video
Updated: Aug 19, 2026

Pre-Chiasmatic, Single Injection of Autologous Blood to Induce Experimental Subarachnoid Hemorrhage in a Rat Model
Published on: June 18, 2021
[Life following acute subarachnoid haemorrhage]
Kirsten E Wik1, Karl-Fredrik Lindegaard, Birgit Brunborg
1Nevrokirurgisk avdeling, Rikshospitalet, Oslo. kirsten.e.wik@rikshospitalet.no
Background:
We studied the outcome after aneurysmal subarachnoid haemorrhage from a patient perspective. We compared outcomes of microsurgical and endovascular aneurysm repair and assessed the impact of gender and age on quality of life.
Material And Methods:
60 patients undergoing repair of a ruptured intracranial aneurysm from January to July 2001 were included consecutively (35 women). Endovascular repair was performed on 39 and microsurgery on 21. The mean age was 55 years. Quality of life was assessed 3 and 12 months after the bleed using WHOQOL-BREF and Rankin score questionnaires, and through interviews (n = 9).
Results And Interpretation:
A total of 40 of 58 patients returned both questionnaires; two died. Twelve months after the bleed, 26 of 44 patients reported a "good" or "very good" subjective quality of life, 3 out of 44 reported a "poor", and 15 of out 44 a "neither good nor poor" subjective quality of life. Males reported a significantly better quality of life (p=0.008). Women reported feeling more depressed and also significantly more symptoms of asthenia, less energy and working capacity. We found no significant differences pertaining to age. Despite moderate disabilities, the respondents generally scored high on quality of life after subarachnoid haemorrhage. The gender differences clearly deserving further investigations.
Related Concept Videos
Hemorrhagic Stroke ll: Pathophysiology
Hemorrhagic Stroke l: Introduction
Secondary Spinal Cord Injury llI: Pathophysiology
Cerebral Edema ll: Pathophysiology
Ischemic Stroke ll: Pathophysiology
Increased Intracranial Pressure ll: Pathophysiology

