Related Experiment Video
Updated: Aug 19, 2026

Cardiac Magnetic Resonance Imaging at 7 Tesla
Published on: January 6, 2019
Coronary arteries at 3.0 T: Contrast-enhanced magnetization-prepared three-dimensional breathhold MR angiography
1Department of Radiology, Northwestern University, Chicago, Illinois, USA.
Insights
Contrast-enhanced coronary magnetic resonance angiography (MRA) at 3.0 T shows improved signal and contrast, enhancing visualization of coronary arteries. This technique is promising for diagnosing coronary artery diseases.
Area of Science:
- Cardiovascular Imaging
- Magnetic Resonance Imaging
- Medical Diagnostics
Background:
- Coronary artery disease diagnosis relies on advanced imaging techniques.
- Magnetic Resonance Angiography (MRA) offers non-invasive visualization of coronary arteries.
- Higher magnetic field strengths may improve MRA performance.
Purpose of the Study:
- To evaluate the efficacy of contrast-enhanced coronary MRA at 3.0 Tesla (T).
Main Methods:
- Nine healthy volunteers underwent 3D, breathhold, segmented gradient-echo MRA on a 3.0-T system.
- Gadopentetate dimeglumine contrast agent was administered.
- Image quality metrics including SNR, CNR, vessel length, lumen diameter, and sharpness were assessed and compared to 1.5-T data.
Main Results:
- Contrast enhancement significantly increased SNR by 53% and CNR by 305%.
- Postcontrast imaging showed increased vessel length and sharpness, with decreased lumen diameter (P < 0.05).
- Compared to 1.5-T, 3.0-T MRA demonstrated enhanced SNR, CNR, and vessel sharpness at higher spatial resolution.
Conclusions:
- Contrast-enhanced 3D coronary MRA at 3.0 T is a promising diagnostic tool.
- Further patient studies are required to establish its clinical utility for coronary artery disease.
Purpose:
To evaluate the efficacy of contrast-enhanced coronary magnetic resonance angiography (MRA) at 3.0 T.
Materials And Methods:
Nine healthy human volunteers were studied on a 3.0-T whole-body MR system. A three-dimensional, breathhold, magnetization-prepared, segmented, gradient-echo sequence was used, with injection of 20 mL gadopentetate dimeglumine for each three-dimensional slab. Imaging parameters were optimized based on computer simulations. Signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), depicted coronary artery length, lumen diameter, and imaging sharpness with contrast agent were evaluated. SNR and CNR were compared to the results from a previous 1.5-T study.
Results:
A 53% increment in SNR and a 305% enhancement in CNR were measured with contrast. Vessel length and sharpness depicted were higher and the lumen diameter was lower (all P values < 0.05) in postcontrast images. Compared to previous results from 1.5-T, the SNR, CNR, and vessel sharpness were enhanced at 3.0 T with higher spatial resolution.
Conclusion:
Contrast-enhanced, three-dimensional, coronary MRA at 3.0 T is a promising technique for diagnosing coronary artery diseases. Patient studies are necessary to evaluate its clinical utility.
Related Concept Videos
Imaging Studies for Cardiovascular System IV: CMRI
Magnetic Resonance Imaging
Radiological Investigation III: Pulmonary Angiogram and PET Scan
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Imaging Studies for Cardiovascular System V: CT
Radiological Investigation II: MRI and Ventilation Perfusion Scan
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...
Imaging Studies for Cardiovascular System III: X-Ray
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
