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Updated: Aug 19, 2026

A Fluorescence-based Method to Study Bacterial Gene Regulation in Infected Tissues
Published on: February 19, 2019
Interacting regulatory networks in the facultative photosynthetic bacterium, Rhodobacter sphaeroides 2.4.1
1Microbiology and Molecular Genetics, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA. Samuel.Kaplan@uth.tmc.edu
Abstract:
Regulation of photosynthetic membrane synthesis in Rhodobacter sphaeroides 2.4.1 is dependent on the interactions of numerous regulatory elements, with two of the most important being the cbb(3) terminal oxidase and the PrrBAC two-component regulatory system. Here, we reveal that the cbb(3) terminal oxidase possesses extensive, additional regulatory activities under anaerobic conditions, and that the PrrBAC system is further involved in the regulation of the expression of more than 20% of the R. sphaeroides genome under anaerobic conditions, extending well beyond functions related to redox gene expression.
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