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Updated: Aug 13, 2026
09:29
A Complete Pipeline for Isolating and Sequencing MicroRNAs, and Analyzing Them Using Open Source Tools
Published on: August 21, 2019
MicroRNA biogenesis: drosha can't cut it without a partner
Yukihide Tomari1, Phillip D Zamore
1Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA.
Current Biology : CB
|January 26, 2005
Abstract:
The ribonuclease Drosha requires a dedicated double-stranded RNA binding protein to convert long, nuclear primary microRNA transcripts into shorter pre-microRNA stem-loops, the cytoplasmic precursors from which mature microRNAs are ultimately excised.
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