Related Experiment Video
Updated: Aug 19, 2026

Intrathecal Application of a Fluorescent Dye for the Identification of Cerebrospinal Fluid Leaks in Cochlear Malformation
Published on: February 29, 2020
Cerebrospinal fluid leak in a premature neonate
Arieh Riskin1, Liana Beni-Adani, Irena Chistiekov
1Department of Neonatology, Bnai Zion Medical Center, The B. Rappaport Faculty of Medicine, Technion, Israel Institute of Technology, Haifa, Israel.
Abstract:
Cerebrospinal fluid (CSF) cranial leaks in neonates are rare, and only four case reports have been published previously. Two of the previous cases were also in preterm newborns delivered at 30 weeks gestation. We present a case of CSF leak in a premature neonate delivered at 30 weeks gestation. Our approach to treatment was different from that previously described. After the initial treatment with local packing bandage failed to stop CSF leakage, local exploration with wound suturing was done, with resultant ceasing of leakage within 12 hours of birth. This case presents a rare complication of CSF leakage caused by internal scalp monitoring. This complication seems to be more frequent in premature babies, thus special consideration should be taken in premature infants before applying such monitoring.
Related Concept Videos
Cerebral Edema ll: Pathophysiology
Cerebrospinal Fluid
CSF Production
CSF is produced mainly in the choroid plexus, a network of capillaries and ependymal cells located within the ventricular system of the brain.
Cerebral Edema l: Introduction
Bacterial Meningitis I: Introduction
Increased Intracranial Pressure ll: Pathophysiology
Brain Abscess l: Introduction

