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[Causes and prognosis of syncope in patients with primary dilated cardiomyopathy]

B Brembilla-Perrot1, C Suty-Selton, D Beurrier

  • 1Cardiologie, CHU de Brabois, Vandoevre-les-Nancy. b.brembilla-perrot@chu-nancy.fr

Archives Des Maladies Du Coeur Et Des Vaisseaux
|January 27, 2005
PubMed

Insights

Syncope in primary dilated cardiomyopathy has diverse causes, with ventricular arrhythmias not impacting prognosis. Left ventricular ejection fraction is the key predictor of mortality in these patients.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Heart Failure Research

Context:

  • Primary dilated cardiomyopathy (DCM) prognosis is debated.
  • Syncope is traditionally linked to increased mortality risk in DCM patients.

Purpose:

  • To investigate the causes and prognostic implications of syncope in primary DCM.
  • To identify key factors influencing outcomes in DCM patients experiencing syncope.

Summary:

  • Sixty-five primary DCM patients (age 31-80) with syncope underwent extensive investigations.
  • Ventricular arrhythmias were found in 35% of cases; other causes included supraventricular arrhythmias and conduction defects.
  • No cause was identified in 23% of patients; tilt testing was positive in 8%.

Impact:

  • During 4-year follow-up, 15% mortality occurred, solely correlated with reduced left ventricular ejection fraction (LVEF).
  • Ventricular arrhythmias did not significantly affect prognosis.
  • LVEF emerged as the most critical prognostic factor in primary DCM patients with syncope.

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