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Serum oxidant/antioxidant balance in exfoliation syndrome
Ayça Yimaz1, Ufuk Adigüzel, Lülüfer Tamer
1Department of Ophthalmology, Mersin University Faculty of Medicine, Mersin, Turkey.
Background:
To evaluate the relationship between the serum oxidant-antioxidant balance and the presence of exfoliation syndrome (XFS) in a prospective study.
Methods:
The study group comprised 27 cases of XFS. Serum concentrations of myeloperoxidase, malondialdehyde, vitamins A, C and E, catalase and total antioxidant were measured and compared with an independent group by t-test.
Results:
Serum myeloperoxidase, vitamins A and E, catalase and total antioxidant parameters were not statistically different among the groups (P >0.05). Serum vitamin C concentrations were significantly lower and malondialdehyde concentrations were significantly higher in cases of XFS when compared with the control group (P=0.008 and P=0.002, respectively).
Conclusion:
An altered oxidant-antioxidant balance may play a role in the pathogenesis of XFS.
