Factors influencing twins and zygosity
Gary V D Hankins1, George R Saade
1Department of Obstetrics and Gynecology, The University of Texas Medical Branch, Galveston, TX, USA. ghankins@utmb.edu
Abstract:
Zygosity is influenced by many factors. Monozygotic twins occur spontaneously in approximately 1 in 250 births and are felt to increase twofold with ovulation induction techniques. Monozygotic twinning also increases in proportion to the number of blastocysts transferred during in vitro fertilisation. In contrast, dizygotic twinning appears to be influenced by race, genetic factors, maternal age, fertility enhancing drugs, folic acid supplementation, and maternal nutritional status.
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