Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Intersurf: dynamic interface between proteins.

Nicolas Ray1, Xavier Cavin, Jean-Claude Paul

  • 1Project Isa, Inria Lorraine, 615 rue du Jardin Botanique, BP 101, 54602 Villers-les-Nancy Cedex, France. nicolas.ray@loria.fr

Journal of Molecular Graphics & Modelling
|January 27, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Quantifying the impact of health service delivery barriers on access to healthcare: a case study of antiretroviral therapy in Mali.

BMJ global health·2026
Same author

Influence of Both La Nina and Island Isolation During COVID-19 on the Epidemiology of Infectious Diseases in New Caledonia.

Epidemiologia (Basel, Switzerland)·2026
Same author

Incidence of Dementia With Lewy Bodies in Salento, Italy: A Population-Based Study.

Neurology·2026
Same author

Incidence and Prevalence of Dementia With Lewy Bodies: A Systematic Review and Meta-Analysis.

JAMA neurology·2026
Same author

Impact of extreme precipitation events on facility-based births in 21 sub-Saharan African countries.

Nature communications·2026
Same author

Incidence of primary progressive aphasia in Salento, Italy: a population-based study.

Alzheimer's research & therapy·2026
Same journal

Efficacy of Tinospora cordifolia bioactives as agonists of Smoothened (Smo) receptor to promote oligodendroglial lineage induction for remyelination-based therapy.

Journal of molecular graphics & modelling·2026
Same journal

Dynamic remodeling of USP28 by the selective inhibitor CAS-010: Insights from DFT and molecular dynamics simulations.

Journal of molecular graphics & modelling·2026
Same journal

Beyond the catalytic site: Voxilaprevir and Pasireotide as repurposed therapeutics for conformational inhibition of ADAR1.

Journal of molecular graphics & modelling·2026
Same journal

A mechanism-guided framework for prioritizing membrane-interaction anti-Vibrio peptides from peptidomics data.

Journal of molecular graphics & modelling·2026
Same journal

A multi-Level Study of 20S proteasome inhibitors: an integrated approach combining chemistry and Modelling.

Journal of molecular graphics & modelling·2026
Same journal

In silico identification of DNMT1 inhibitors from the PlantCyc database through computational approach to assess the anti-cancer potential of nutraceutical compounds in breast cancer.

Journal of molecular graphics & modelling·2026
See all related articles

This study introduces a fast algorithm for protein docking that visualizes protein interactions using 2D maps. The method efficiently extracts interface surfaces and updates them in real-time for better analysis.

Area of Science:

  • Biochemistry
  • Structural Biology
  • Computational Biology

Background:

  • Protein-protein interactions are crucial biological processes.
  • Visualizing protein interfaces aids in understanding docking and predicting binding affinity.
  • Current methods for interface analysis can be computationally intensive.

Purpose of the Study:

  • To develop a fast algorithm for extracting protein interface surfaces.
  • To generate valid and low-distortion 2D interaction maps from these surfaces.
  • To enable real-time updates of the interface as residues move.

Main Methods:

  • An algorithm was developed to extract protein interface surfaces.
  • A 2D interaction map is created from the extracted surface.

Related Experiment Videos

  • The algorithm includes a pre-computed component for real-time surface updates.

    • Main Results:

    • A very fast algorithm for protein interface extraction was achieved.
    • The method generates valid and low-distortion 2D interaction maps.
    • The interface surface can be updated in real-time.

    Conclusions:

    • The developed algorithm offers an efficient way to visualize and analyze protein-protein interaction interfaces.
    • This approach facilitates the understanding of protein docking processes and the quality assessment of docking simulations.
    • Real-time updates enhance the utility for interactive analysis and prediction of docking affinity.