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Related Experiment Videos

Sensitivity encoding for diffusion-weighted MR imaging at 3.0 T: intraindividual comparative study.

Christiane K Kuhl1, Jürgen Gieseke, Marcus von Falkenhausen

  • 1Department of Radiology, University of Bonn, Sigmund-Freud-Strasse 25, D-53105 Bonn, Germany. kuhl@uni-bonn.de

Radiology
|January 27, 2005
PubMed
Summary

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Sensitivity Encoding (SENSE) parallel imaging at 3.0 T significantly enhances diffusion-weighted MRI quality and diagnostic confidence for ischemic lesions. This technique reduces artifacts, improving lesion detection compared to conventional methods.

Area of Science:

  • Radiology
  • Medical Imaging
  • Neurology

Background:

  • Diffusion-weighted (DW) magnetic resonance (MR) imaging is crucial for diagnosing ischemic lesions.
  • Conventional phase encoding in DW MR imaging can be limited by image distortions and artifacts.
  • Sensitivity Encoding (SENSE) is a parallel imaging technique that accelerates MR acquisition.

Purpose of the Study:

  • To prospectively evaluate if DW MR imaging with SENSE at 3.0 T improves image quality.
  • To assess if SENSE enhances diagnostic confidence and accuracy for ischemic lesions compared to conventional DW MR imaging.
  • To compare SENSE and conventional phase encoding in terms of image quality, signal-to-noise ratio, and lesion contrast.

Main Methods:

  • Eighty-five patients underwent two DW MR imaging scans at 3.0 T: one with conventional phase encoding and one with SENSE (reduction factor of three).

Related Experiment Videos

  • Image quality, signal-to-noise ratio, relative signal intensity, and lesion contrast were compared between the two techniques.
  • Two neuroradiologists assessed diagnostic accuracy and confidence in detecting apparent diffusion coefficient (ADC) lesions.

    • Main Results:

    • SENSE-based DW MR imaging yielded significantly higher image quality scores due to reduced distortions and blurring (P < .001).
    • Diagnostic confidence in identifying or excluding lesions was significantly higher with SENSE (P < .001).
    • Small microembolic lesions, missed with conventional imaging due to susceptibility effects, were detected with SENSE.

    Conclusions:

    • Parallel MR imaging with SENSE is feasible and effective at 3.0 T for DW imaging.
    • SENSE significantly improves image quality by reducing susceptibility-induced signal intensity changes and image blurring.
    • SENSE leads to significantly improved diagnostic confidence in the identification and exclusion of ADC changes indicative of ischemia.