Cytokines and endometriosis
J Markowska1, M Kowalska, M Gogacz
1Karol Marcinkowski University School of Medicine, Poznan, Poland.
Introduction:
Abnormal expression of cytokines is considered to be involved in the pathogenesis of endometriosis.
Material And Methods:
In 63 women with various stages of endometriosis preoperative levels of cytokines, including IL-6, IL-8, BVEGF, b-FGF, of TNF RI and TNF RII were analysed employing ELISA tests (R&D kits).
Results:
In the sera of endometriosis patients significantly augmented levels of IL-6 and of b-FGF were detected as well as a trend for elevated IL-8 levels.
Conclusion:
Elevated serum levels of cytokines may show poor correspondence to the localized pathological process. Endometriosis would find a stricter reflection in cytokine levels in fluids or tissues of the pelvis minor.
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