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Updated: Aug 19, 2026

Improved Home Blood Pressure Control by CT-guided Ozone-mediated Renal Denervation for Patients with Resistant Hypertension
Published on: June 6, 2025
Provocative results suggest lower BP targets may be advisable for CAD patients
Insights
For patients with coronary artery disease (CAD), the choice of antihypertensive drug significantly impacts reduced morbidity and mortality. Physicians should carefully consider drug selection for better blood pressure (BP) management.
Area of Science:
- Cardiology
- Pharmacology
Background:
- Established coronary artery disease (CAD) necessitates careful management of blood pressure (BP).
- The selection of antihypertensive medications may influence patient outcomes beyond BP control.
Purpose of the Study:
- To investigate the impact of antihypertensive drug choice on morbidity and mortality in patients with established CAD.
- To assess whether specific antihypertensive agents offer differential benefits in CAD management.
Main Methods:
- Analysis of results from the CAMELOT trial.
- Evaluation of morbidity and mortality data based on antihypertensive drug usage.
Main Results:
- The choice of antihypertensive drug demonstrated a significant effect on reducing morbidity and mortality in patients with CAD.
- Specific drug choices may be linked to differential patient benefits.
Conclusions:
- Antihypertensive drug selection is a critical factor for improving outcomes in CAD patients.
- Further research is warranted to optimize antihypertensive therapy in this population.
- There is potential for improved BP management even within current therapeutic targets.
Abstract:
Provocative new findings suggest that for patients with established CAD, the answer is yes. And physicians might want to carefully consider which antihypertensive drug to use in such patients as well. Results from the just-released CAMELOT trial show that significant benefit in reduced morbidity and mortality could be riding on this decision. While more research on this matter is clearly in order, experts contend there is already ample room for improvement in BP management--even with current targets.
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Special considerations while measuring blood pressure
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.