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Utility of routine follow-up defibrillator threshold testing in congenital heart disease and pediatric populations
Elizabeth A Stephenson1, Frank Cecchin, Edward P Walsh
1Department of Cardiology, Children's Hospital, Boston, Boston, Massachusetts 02115, USA.
Insights
Routine defibrillation threshold (DFT) testing for implantable cardioverter defibrillators (ICDs) in pediatric patients with congenital heart disease is valuable. Prompted DFT testing identified significant device abnormalities, highlighting its clinical importance in this unique population.
Area of Science:
- Pediatric Cardiology
- Biomedical Engineering
- Electrophysiology
Background:
- Routine defibrillation threshold (DFT) testing for implantable cardioverter defibrillators (ICDs) in adults is increasingly questioned.
- Pediatric and congenital heart disease populations have a higher incidence of ICD lead failure.
- The necessity of follow-up DFT testing in these unique patient groups requires investigation.
Purpose of the Study:
- To investigate the utility and yield of follow-up defibrillation threshold (DFT) testing in pediatric patients with congenital heart disease.
- To compare the outcomes of routine versus clinically prompted DFT testing in this population.
Main Methods:
- Retrospective review of 155 implantable cardioverter defibrillator (ICD) recipients at a single center.
- Analysis of patients who underwent one or more follow-up DFT tests, categorized into "routine" and "prompted" groups.
- Evaluation of reprogramming or hardware changes resulting from DFT testing.
Main Results:
- A total of 79 follow-up DFT procedures were analyzed (58 routine, 21 prompted).
- Clinically significant changes requiring reprogramming or system revision were detected in 24% of all procedures.
- Prompted testing showed a higher yield of abnormalities compared to routine testing.
Conclusions:
- Follow-up defibrillation threshold (DFT) testing reveals a high rate of abnormalities in pediatric and congenital heart disease ICD recipients.
- Clinically indicated (prompted) DFT testing is particularly valuable for assessing device function and ensuring patient safety.
- These findings support the importance of targeted DFT testing in this high-risk population.
Introduction:
Recent studies have suggested that routine defibrillation threshold (DFT) testing of implantable cardioverter defibrillators (ICDs) in adults may not be necessary. The congenital heart disease and pediatric populations are a unique group of ICD recipients having a higher incidence of lead failure. We investigated the utility of follow-up DFT testing in this population.
Methods And Results:
The records of 155 ICD recipients at one center were retrospectively reviewed, and patients having one or more follow-up DFT tests were analyzed. The patients were divided into two groups. The "routine" group consisted of 58 follow-up DFT procedures in 46 patients, without known changes in ICD parameters. The "prompted" group consisted of 21 follow-up DFT procedures in 18 patients, motivated by clinical concerns about changes in ICD lead status. Of 58 "routine" DFTs performed at a mean postimplant duration of 32 +/- 23 months (range 2-78), 7 (12%) had reprogramming, and 1 required a hardware change as a result of the testing. Of the 21 "prompted" DFTs performed, 7 required device reprogramming, and 3 required hardware upgrade. Overall, 19 (24%) of 79 procedures detected clinically significant changes, requiring reprogramming or ICD system revision. No complications were seen from follow-up DFT testing.
Conclusion:
A high rate of abnormalities was found at follow-up DFT testing in this population, especially in the group of patients with clinically prompted testing. Clinically indicated DFT testing, as expected, has a high yield of important information on device function in congenital heart disease and pediatric populations.
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