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Updated: Aug 19, 2026

Using Retinal Imaging to Study Dementia
Published on: November 6, 2017
Defining the diagnosis of vascular dementia
Kelly Davis Garrett1, Robert H Paul, David J Libon
1Utah State University and LDS Hospital Neurospecialty Rehabilitation Unit, Salt Lake City, UT 84143-0001, USA. kelly@drexel.edu
Insights
This study proposes refining vascular dementia (VaD) diagnosis by characterizing vascular changes, using process-based cognitive assessments, integrating MRI data, and considering "vascular cognitive impairment, no dementia" for early stages.
Area of Science:
- Neuroscience
- Neurology
- Psychology
Background:
- Vascular dementia (VaD) is a complex term for behavioral changes linked to cerebrovascular issues.
- Current literature lacks consensus on VaD's neuropsychological characteristics and their relation to specific vascular changes.
Purpose of the Study:
- To address the lack of consensus in VaD diagnosis and assessment.
- To propose recommendations for refining the clinical assessment and diagnostic decision-making for suspected cerebrovascular changes.
Main Methods:
- Recommending detailed description of vascular changes to predict neuropsychological profiles.
- Advocating for a process-based assessment of cognitive constructs alongside test scores.
- Suggesting integration of direct MRI observations and collateral data.
- Proposing the term "vascular cognitive impairment, no dementia" for prodromal VaD.
Main Results:
- Characterizing vascular changes can aid in predicting specific neuropsychological profiles of VaD subtypes.
- A process-based cognitive assessment approach offers a more nuanced understanding of VaD profiles.
- Integrating neuroimaging (MRI) and other data improves diagnostic accuracy.
- Identifying "vascular cognitive impairment, no dementia" can help diagnose prodromal stages.
Conclusions:
- Refined diagnostic criteria and assessment methods are crucial for accurate VaD diagnosis.
- A multi-faceted approach combining vascular pathology, cognitive processes, and neuroimaging is recommended.
- The proposed framework aims to improve the understanding and management of vascular cognitive disorders.
Abstract:
Vascular dementia (VaD) is a heterogeneous term that has evolved to describe the behavioral syndromes associated with a variety of clinical and neuropathologic changes. As such, the VaD literature lacks a clear consensus regarding the neuropsychological and other constituent characteristics associated with various cerebrovascular changes. We address the issues articulated by Paul and colleagues (Paul, Garrett, & Cohen, 2003), by offering four recommendations to refine the clinical assessment and diagnostic decision-making process of individuals with suspected cerebrovascular changes: (a) Describing the nature of vascular changes may facilitate predictions regarding the neuropsychological profile of subtypes of VaD; (b) employ a process approach to assessment, measuring cognitive constructs in addition to test scores to describe the neuropsychological profiles of types of VaD; (c) integrate direct MRI observations of the brain and other collateral data in the diagnostic process; and (d) consider using "vascular cognitive impairment, no dementia" for suspected prodromal VaD.
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