Bispectral index as an indicator of cerebral hypoperfusion during off-pump coronary artery bypass grafting

Thomas M Hemmerling1, Jean-François Olivier, Fadi Basile

  • 1From the Perioperative Cardiac Research Group (PECARG), Departments of Anesthesiology and *Cardiac Surgery, Centre Hospitalier de l'Université de Montréal (CHUM), Hôtel-Dieu, Université de Montréal, Montréal, Québec, Canada.

Anesthesia and Analgesia
|January 28, 2005
PubMed

Insights

Bradycardia and hypotension are common during off-pump coronary artery bypass grafting (OPCAB). Bispectral index (BIS) monitoring may indicate reversible cerebral hypoperfusion during OPCAB surgery.

Area of Science:

  • Cardiology
  • Neurology
  • Anesthesiology

Background:

  • Off-pump coronary artery bypass grafting (OPCAB) is associated with hemodynamic instability, including bradycardia and hypotension.
  • Cerebral hypoperfusion is a potential complication during OPCAB, posing risks to neurological function.

Observation:

  • A case study involving a 58-year-old patient undergoing OPCAB presented with a sudden decrease in Bispectral Index (BIS) from 45-50 to 0 during distal grafting of the left circumflex artery.
  • This sudden drop in BIS occurred concurrently with bradycardia and hypotension.

Findings:

  • The patient experienced reversible global cerebral hypoperfusion, indicated by the significant drop in BIS.
  • Immediate neurological evaluation post-surgery revealed no deficits, and the patient had an uneventful recovery and discharge.

Implications:

  • Bispectral Index (BIS) monitoring can serve as a valuable indicator of cerebral hypoperfusion during OPCAB procedures.
  • Early detection of cerebral hypoperfusion through BIS monitoring may allow for timely interventions to prevent neurological sequelae in patients undergoing OPCAB.

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