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Treatment of Ligament Constructs with Exercise-conditioned Serum: A Translational Tissue Engineering Model
Published on: June 11, 2017
Combined effects of estrogen and mechanical loading on anterior cruciate ligament fibroblast biosynthesis
1Sports Medicine Research Center, Department of Orthopedic Surgery, Baylor College of Medicine, 6550 Fannin Street, Suite 451, Houston, TX 77030, USA.
Thescientificworldjournal
|January 28, 2005
Abstract:
For some time, estrogen has been suspected to play a negative role in anterior cruciate ligament (ACL) fibroblast biosynthesis; however, reports on this issue have been controversial. In a recent study, our group demonstrated a negative combined effect of estrogen and mechanical loading on the gene expression of major extracellular matrix component molecules in ACL fibroblasts.

