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LINAC radiosurgery in skull base meningiomas
R Deinsberger1, J Tidstrand, H Sabitzer
1Department of Neurosurgery, Klagenfurt General Hospital, Klagenfurt, Austria. r.deinsberger@kh-st-poelten.at
Minimally Invasive Neurosurgery : MIN
|January 28, 2005
Summary
LINAC radiosurgery effectively treats benign skull base meningiomas, achieving a 97.2% tumor control rate with minimal side effects. This approach enables less invasive treatment strategies, improving patient quality of life.
Area of Science:
- Neurosurgery
- Radiation Oncology
- Oncology
Background:
- Benign skull base meningiomas require effective treatment strategies.
- LINAC radiosurgery has become increasingly accessible for these tumors.
Purpose of the Study:
- To evaluate the efficacy and safety of LINAC radiosurgery for benign skull base meningiomas.
- To assess the impact of LINAC radiosurgery on treatment strategies and patient outcomes.
Main Methods:
- Retrospective analysis of 37 patients treated with LINAC radiosurgery between 1996 and 2003.
- Treatment involved a combination of University of Florida and Radionics X Knife systems.
- Doses ranged from 12.8 to 18 Gy, with a median volume of 5.9 mL.
Main Results:
- Tumor control rate of 97.2% observed over a median follow-up of 66 months.
- Significant tumor size reduction in 32.4% of patients, decreased enhancement in 29.7%.
- Low morbidity with only 5.6% experiencing transient neurological worsening.
Conclusions:
- LINAC radiosurgery is an effective treatment for skull base meningiomas.
- It facilitates a less aggressive surgical approach, improving quality of life.
- Combining microsurgery and radiosurgery achieves high tumor control with acceptable morbidity.